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Modafinil is a eugeroic that’s commonly used to treat cases of narcolepsy in adults. It’s described as a “wakefulness-promoting agent”, and belongs to the nootropic and psychoanalytic families of medicines.
Those with narcolepsy often struggle with staying awake during the day, no matter how much sleep they’ve had at night. It’s a medical condition that affects around 30,000 people in the UK alone and can be a frustrating and embarrassing thing to live with, and can also cause temporary muscle weakness (called cataplexy).
Modafinil is very effective at reducing the symptoms of narcolepsy, and often improves the quality of life for sufferers. Modafinil isn’t a cure for narcolepsy, but it is an effective treatment that makes the condition easier to live with.
What is Modafinil
Modafinil is a legal medicine that is licenced in most countries around the world for the treatment for narcolepsy in adults. You can buy modafinil in its generic form, or also as the branded version named Provigil in the United States and Modiodal in the European Union. (they are identical).
Despite this, some patients prefer to use cheap generics from India, and vice versa.
Modafinil helps those with narcolepsy to stay awake. It isn’t fully understood how it works yet, but it’s thought to stimulate a part of the brain and affect several neurotransmitters, especially those that are involved with sleep and wakefulness.
However, one theory about modafinil is that it increases the amount of dopamine – a chemical that’s responsible for regulating sleep and wakefulness. Whilst the mechanism of modafinil isn’t completely understood, what we do know is that it significantly reduces feelings of sleepiness and fatigue, meaning that those struggling with narcolepsy can lead a normal life without as many sleep attacks.
How long does modafinil take to kick in
For most people, modafinil only takes around 30 minutes to an hour to start working.
Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder.
Modafinil is a very effective cognitive enhancer. It also has its use in those working awkward hours (shift work disorder).
Many sites offer Indian generics. iModaf offers quality Modiodal made in Europe. Modiodal is the brand name used in Europe for the American original modafinil product Provigil.
Performance boosting eugeroic modafinil is the world’s first safe ‘smart pill’
Increasingly taken by healthy people to improve focus before exams, after a comprehensive review researchers say modafinil is safe in the short-term.
Modafinil is the world’s first safe “smart drug”, researchers at Harvard and Oxford universities have said, after performing a comprehensive review of the drug. They concluded that the drug, which is prescribed for narcolepsy but is increasingly taken without prescription by healthy people, can improve decision- making, problem-solving and possibly even make people think more creatively.
While acknowledging that there was limited information available on the effects of long-term use, the reviewers said that the drug appeared safe to take in the short term, with few side effects and no addictive qualities.
Modafinil has become increasingly common in universities across Britain and the US. Prescribed in the UK as Provigil, it was licensed in 2002 for use as a treatment for narcolepsy – a brain disorder that can cause a person to suddenly fall asleep at inappropriate times or to experience chronic pervasive sleepiness and fatigue.
Used without prescription, modafinil is what is known as a smart drug – used primarily by people wanting to improve their focus before an exam. A poll of Nature journal readers suggested that one in five have used drugs to improve focus, with 44% stating modafinil as their drug of choice.
A new review of 24 of the most recent modafinil studies suggests that the drug has many positive effects in healthy people, including enhancing attention, improving learning and memory and increasing something called “fluid intelligence” – essentially our capacity to solve problems and think creatively. One study also showed that modafinil made tasks seem more pleasurable. The longer and more complex the task tested, the more consistently modafinil conferred cognitive benefits, the authors of the review said.
The review points out that negative effects – including one study that showed that people already classed as creative saw a small drop in creativity – were reported in a small number of tasks, but never consistently. It added that the drug exerts positivd effects on mood, and only causes minor side effects such as nausea, headaches and anxiety, although these were also reported by people who took a placebo drug.
Other proposed stimulants, such as Ritalin and Adderall (Amphetamine), prescribed for ADHD, have many negative side effects, said Anna-Katharine Brem, co-author of the review, published today in the journal European Neuropsychopharmacology. “Modafinil seems to be the first ‘smart drug’ that is safe for healthy people.”
She emphasised that although the drug is not thought to be addictive, its long-term effects have not been studied. “It would be difficult to get ethical approval to test the effects of taking this drug in the long term,” she said.
Peter Morgan, at Yale School of Medicine, says there is substantial evidence that other cognitive enhancers, such as caffeine or nicotine, have benefited from short-term use, but that those benefits are erased by long-term use, and are rather replaced by deficiencies in cognitive performance.
The effects of modafinil on the brain are complex and not well understood. One promising theory is that the drug increases blood flow to brain areas serving attention and learning. It might also enhance brain activity in areas thought to act as “conductors”, which manage skills like memory, reasoning and problem-solving.
“Modafinil is the first real example of a smart drug which can genuinely help, for example, with exam preparation,” said Guy Goodwin, president of the European College of Neuropsychopharmacology. “Previous ethical discussion of such agents has tended to assume extravagant effects before it was clear that there were any. If correct, the present update means the ethical debate is real: how should we classify, condone or condemn a drug that improves human performance in the absence of pre-existing cognitive impairment?”
Goodwin points out that drugs are approved to treat illnesses if they are effective and safe. The manufacturers of modafinil will not attempt to extend the licence to exam doping and there would be no precedent for handling such an application if they did, he said.
“That leaves us in uncharted territory.
Brem and her co-author Ruairidh Battleday think that time for debate has come. “For the first time, we have an agent without serious side effects showing the benefits which we haven’t had before.”
“We’re not saying ‘go out and take this drug and your life will be better’,” said Brem. “It is time for a wider debate on how to integrate cognitive enhancement into our lives. We need to explore the ethics, and scientist, politicians and the public need to be involved.”
The action of modafinil on increased motivation (study).
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Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as obstructive sleep apnoea. It helps one stay awake during work hours and particularly suitable for work schedules that prevent ‘normal’ sleep habits (shift work sleep disorder). Buy Modafinil (Modiodal Provigil) Online here at iModaf. Authentic Modafinil.
Modafinil does not take the place of getting enough sleep. It is not known how modafinil works to keep one awake and energetic. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.
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